We might have a problem.

It looks like somebody's on the rag.

You seem to know a lot about this stuff.

You seem to know a lot about this stuff. Have you been on a date before? / Похоже, ты много об этом знаешь. Ты раньше был на свидании?

It looks like you didn't get much sleep last night.

It looks like I am in the wrong place.

It looks like we're gonna have to pack it up.

I guess I'm wrong again.

It's not like you at all.

You don't seem to understand.

That doesn't seem right.