We might have a problem.

It looks like somebody's on the rag.

You seem to know a lot about this stuff.

You seem to know a lot about this stuff. Have you been on a date before? / Похоже, ты много об этом знаешь. Ты раньше был на свидании?

It looks like you didn't get much sleep last night.

- It looks like you didn't get much sleep last night. / Похоже, ты не выспался прошлой ночью.

- I stayed up all night. I had to finish my report. / Я всю ночь не спал. Должен был закончить отчет.

It looks like I am in the wrong place.

It's not like you at all.

You don't seem to understand.

That doesn't seem right.

No one seems to care.

I think I'm going to be sick.

- You have red and and a runny nose. Is this your allergies or something? / У тебя красные глаза и насморк. Это аллергия или что-то в этом роде?

- No, I don't have any allergies. I think I'm going to be sick. /  Нет, у меня нет аллергии. Похоже, я заболеваю.